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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80535f74ac3eb7f8f802dce4431642d6c5ff8a5a7182f901657e7147b437efe' 
  AND token = 'bxwA+V5oJufL/SBPwKTpupZ4uwh9wt072Bb2xhZMBfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}