SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb64f08bc88c7d784b6eb7ebbdebad6a48e8a0e0f38f8be2ee180c454a5c56b' 
  AND token = 'spzd9FTgTWniCJRCWNWU0PzNjd9rTUIVRt1FJZEIJ1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}