SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe41d9e81f295e5d09250d147895a6708193773f4e296b8b3eb891bc93fa70e1' 
  AND token = 'VMnxIj1lLeqAy7tmS2a5/0T71av4VmQ89+ckXMrP/fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}