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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1868fe3ff96611e5bd9b89ac899cf8aaae59adcb954d0573ae0d7193df87245' 
  AND token = 'MhVizzOlRd7OdREVK4Zkpw5YVwI/noOHysdyI24503w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}