SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62135bfd06f70cc5c5a83566ba48bc4818c3b288a41547a41f99fba0774e5922' 
  AND token = '22g9Gxs/u+4JjZ64UhYBjDl/7YjhwMJHPPLBbNUeFy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}