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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741bb8c987b46cb275dad99cc58bde4faf0c1161cdb378fcb2c4a07ae73b370e' 
  AND token = '8rjreY7KbL8MMXvBW4u+Wbp2tABjeC372FLfTmmS5Ac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}