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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '027d6a3091bec1eead1103a9bfe36ca7727573f5138edc17eca61301f7017c36' 
  AND token = 'q+0uQBzMuim5yjm3IhlY50pgMLdyGpFWXJs8ObhVYHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}