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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2446f67b1ca7cb1bc08856e27bba70cd67e1d5c6e067d3b85a16f0e458faee04' 
  AND token = 'DppwkNX9nKY6kFOP2TddtHjv21oLA/3R+MZl4qE0hXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}