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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec09f5493fb77b8ea35539e4894680cc7b04d4fcc6df9460e342a1ee083f51d' 
  AND token = 'gdIm/pxLkx8TtCVz92GDOXWIhxgxohD5ssoXGW0awb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}