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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f39b5a2dd5fd728fa242fe5537068a66b740439f257b23c32f5024f5e491648f' 
  AND token = 'vHtKhwVx9WWU9hDP2yR3eUMcKmmBoa2gM7Xqj6tUoPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}