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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589cfba61bd59d56eae0479ea02c643d268ae9d5d121439832ff227f2921ee61' 
  AND token = 'kYS3F0pevjoCJLEYgD7TsUhPJrCtyVcNWYwMxCceqjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}