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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5dacb565ef9254d3a1a78328bd9eddb7c90940f09d88cb7d61ed3389babe621' 
  AND token = 'd/NAZmVu0la8Uo7YEp97nSS9EuyAvwE6fzACxV65gM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}