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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2799ca319383ec2fb4dd2003577b1e57642c08803249b9f071d564924a04222' 
  AND token = 'YP0kyHin7/hAeQ1KDehPKHdanQMkBYmq1T8+S/dm5Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}