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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f59adca31d8a67b4e1986d0a809192f3975a9e59a828749be5a62df35e1310ea' 
  AND token = 'TcOS4YzGouNcdH7BUIQNeCKM+IU7rNNo0cc/DrgUQ7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}