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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb829d3e72a04820d3427853bf60c0861b5219e46d2e700bd8f596394ea35c1' 
  AND token = 'QWywbw7nn7//l96OkAYjzu7+v0WUF5wTdxm97B4DsvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}