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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863ec8bb3278c4b9ff73916cb6f5c184c0b11eafde1c35c01775fb0c1c94757f' 
  AND token = 'Kr4ERJIjXnbDfRNmv09QiDG8i14oaXf9CmE4lUqRQeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}