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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd91a0d060a09f2066d10be2b8b2cb880a489673b879f315519ef038aaa8ac5' 
  AND token = 'kvT9bqgVA65QtCBS8+4QFqEz7WbMrETf/E8de8BlQ9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}