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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4f02923b888daa4b678efdcdcbbe0a697ee8923fb4e7b8e067ce01379a51458' 
  AND token = 'u/HfE0+8r3b32iV9Mun16z+9XRiANLovNDyR7uqPNLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}