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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d2fbc240e7323b61fb34e70c485b911e83997b950c8f67f41197e3f204b468' 
  AND token = 'kdOPNUqmw8g9aJRopRrqaPgyx+RufqBl726Rd3cxWGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}