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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52166187563f11e8f71c8687897f05299a81e8d14bd69d7d96a7c16f0b10641e' 
  AND token = '90K0tlL94ojUMHV6fyE3Hlwl+I/hADF0+GgS79w3f2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}