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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8654e8d9ba7c3e1b10b715480e859a537ca2630ddfd974a853118e1879bc2ca2' 
  AND token = 'gLFVRASXRWgKcHD6a2eWiWMsufFFwyLw4gNBXuCdt9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}