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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390b935c5e776eb8b67cf73adadeea64aa991ae382df31d7f10207f401b050cb' 
  AND token = '4GRw/1v/gk6PKrxa3c0M0nwvGNf4+8zPpS2jfu6XXlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}