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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eba49d090a5bf3594f3bbd11a919e12a86bb47f1260bd7f2c962d6ed68538616' 
  AND token = 'AWj3+KjCjqxNrFwZcxflJJsH4+UrneDsZG9NWVb7dEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}