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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '858c886c5ff61606bfed2cbe04eaa2a6c841da1815dfa8405fe68c1ad9b38a3c' 
  AND token = 'cbDjJznCATuXWVbMk6iIDdSpKGDk1uf/Aq3mz8pZnPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}