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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de525807f75ef5f536938aaae55e0f7f335cb3f997fab9f444f52c6415a6bcc' 
  AND token = '06Oy36ygiIWsK5kfa9m1qlqO+W2uvw7V/7KyqkK+2jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}