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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a646dfd0861436f632da38d77c5aaba66495044823c44d9fe1e4b4609267084' 
  AND token = 'D56+Hg9eAiyxGNLdc+nujR6QC0RWf1/DP0P8ao7s8S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}