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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1023ba65328c5dfc7adcb97e5c9191f5afb02404ca562583ccf43b5ac337906c' 
  AND token = '0TLwphOqwFS0mx2ZWMwJBd+YrVMrkpeFnbCW4EwV7ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}