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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d0393f074d6c998fc26f9a85d9e8632d89c83590790e67c3206d971f6af77e' 
  AND token = 'qcfSXWBsuP971OB7TtgB1b10BcuL3MHz555LFiFc8fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}