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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecce539f6d4854350d3b3406176d0a7af2f3d6a2a25db98c0aed5338d4e307f' 
  AND token = '6MsWlls/TAsCLP8Qy4E7q7vOBSce8BCHc1sac0Gnj74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}