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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc87653ac895b157ab0452332049be7ad4a1a27275e999dd9dbc7c810948956' 
  AND token = 'QS4BIk+V/hlMCoDlVXV+2b8k9DDgS+o/XKtJCcEkyAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}