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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e922854a4a41b27d74fc564d1e854d1cd490871ededabe6352375e70332b4e' 
  AND token = 'GjwI5CLM5FjdkUN3QoGAhVkD8OLNCj1S4+sBKezF8Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}