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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2edc205604b4a751c7659dfcb2b4337a23e24c24e1e6b4749be3f2ce5e7d7cdc' 
  AND token = '+yJPcFM3x7AfTP8PkKElPdLlwR3KvmAMnJUkqe3nS3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}