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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1c86faed8cc7a070252f1262ac407285ae34a5bec7cfb8ef289bf3e3ceece6' 
  AND token = '7w9IxfDpDrjnKK+Ba8iO/q6CNCata0OD4DNLgmwlf+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}