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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e81f766d1e0b27ccabaf96e8c1d5debc599420a11bace84c52af0b190a5169f' 
  AND token = 'dNqJvDmX/XNYK0HslJJYRIgVR4399x7rWRoeBDxM1lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}