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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff3f18284881660a8bfbe9b970a7ac04b0f20f8b59f8fe8e4315c38c34166363' 
  AND token = 'Hd1hkhEitqITViwUrXYcQfHVv1BaIswmv1iw33ufSaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}