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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758896a0e9511f9492910c4051e50bd45c13ec4f9bd256674c43b214d4ce64b3' 
  AND token = 'TSVE1I10Tqu/UMjZTB1qX9aF1h+mTUZZVjAWZ+GiJ5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}