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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf3b990ec160c6b0340b0965a12cb8b3152e9484f12f43d2682ac6beae0e527' 
  AND token = 'ppWCPy3PXxofabrZb7Bjnz5zT+KVe166HW8nnN28UPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}