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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b20926a3940fe7dec193d52da2a5f0cfb270e9a232465be8048de9083ff2b204' 
  AND token = 'NlRktWe+NTJ+aMKKy7MTdWOfFZFzXBwBxLhlp3zJSrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}