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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b12037d3c1368342dd7deccac167820aeb1c38657751eab2eb23ac0f51a489' 
  AND token = 'Hzb6fP1nUMfTN9SwWrKUiC9t8APGO5g6j/OGqiILYSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}