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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d0fdddd4c262a2ada560f927f49d9890fc61c5b8781ca2c0c346d6b8595adb' 
  AND token = 'n3Q/B/P8di26H5lTEDIXPfVFeJZpJh58mFn2Rdy+Yuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}