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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7532c70fe974115f27e18650826a679d178b9754c8a1821e9397675a51ba11e2' 
  AND token = 'Hw2NG76GDEtO4Fa9iCztpu4taT4cQ0Ps1T1PpamrRII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}