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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b75409cbc03ec11b251920cd85a3c160c74ffe3a8efdd0e6a38e3c24c0218cce' 
  AND token = 'Quv7ADA/LSOpfN0tlYd3knJSYuY0JOSROSvgkc7gTDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}