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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a048b00248ef1c8d5602c1ef5a6885d88a2a061b4a048b1f9f521856ea64bdcf' 
  AND token = 'ZbR2kLDmHqIKmFbkCL/JanJxxGCPRr7dL9BaCL+dWBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}