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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88863e551dd5d27e022a0cd7397eab87cc66aea48ef36ceb8b7df47649617a2c' 
  AND token = 'Awi+iZ+CkLHcR9JsvDtykgCuVxo/9pjb/BfTia0DD5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}