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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aad5f6bb4287eea01a513fb119ec1d46332203ab55779f4f3945181523da74e' 
  AND token = 'chQLaw1kuQl36ikwM7FrTZOjtpiHU+55h7jiICP1chk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}