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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fa311d078804551f7cf9b6e1ebe63ee75fa1005da5003e045fa578d3abb67ad' 
  AND token = 'YDSPGI9b3Rih2KLPEq/QkIPmnvQvboedh7kKIOP8UdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}