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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1a2d5ca41c5783f670c8a9d4e8691c740120b2d1826a0d43ca9a06acfccdd8' 
  AND token = 'UpTTz5M50FfPXrvMKeF0NB+pJ1GDPG48m0TpXkYpVxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}