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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c42a44f9ff59573e016c6365f52f610783de60d8d64567963c230ee480fc50' 
  AND token = '+IPYAL5BZMi3FPgmI/NrOP2ykEhK3C+fI3MFe8IvKJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}