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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc6d139cfbda3a3f0e2735e35f27bfe457f067039f3969d2febd8b6cd41ae644' 
  AND token = '2InaM6HxpBaTfK+byluPNCzeA6BZCRP3Wq5mtcxJXQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}