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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf5d2d023fcf4930a67b47b18054315c2d9c8535c3bf8506e028444d3006b4c9' 
  AND token = 'mdk5fKeSmJd1L48KMDTgZC99pLJRLZYV/IrxIVkEnL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}